NAD+

NAD+ is an essential coenzyme found in every living cell, central to energy metabolism, DNA repair, and cellular signaling. As a critical substrate for sirtuins and PARP enzymes, it sits at the intersection of longevity research, mitochondrial biology, and metabolic health, making it one of the most researched compounds in aging science today.

NAD+ serves as a key electron carrier in mitochondrial oxidative phosphorylation, directly fueling ATP production. It also acts as a substrate for sirtuin deacetylases (SIRT1-7) and PARP enzymes, both central to DNA damage repair, gene expression regulation, and cellular stress response. NAD+ levels decline significantly with age, driving substantial research interest in its restoration.

Research Areas: Mitochondrial energy production · DNA repair & genomic stability · Sirtuin & longevity pathway activation · Metabolic regulation · Neuroprotection · Cellular senescence & aging biology

For research use only. Not for human consumption.